Background. There continues to be uncertainty on the ideal treatment of pruritus in chronic liver disease. The aim of this study\nwas to gather the latest information on the evidence-based management of pruritus in chronic liver disease. Methodology. A\nliterature search for pruritus in chronic liver disease was conducted using Pubmed and Embase database systems using the MeSH\nterms ââ?¬Å?pruritus,ââ?¬Â ââ?¬Å?chronic liver disease,ââ?¬Â ââ?¬Å?cholestatic liver disease,ââ?¬Â and ââ?¬Å?treatment.ââ?¬Â Results. The current understanding of the\npathophysiology of pruritus is described in addition to detailing research into contemporary treatment options of the condition.\nThese medical treatments range from bile salts, rifampicin, and opioid receptor antagonists to antihistamines. Conclusion. The\nburden of pruritus in liver disease patients persists and, although it is a common symptom, it can be difficult to manage. In recent\nyears there has been greater study into the etiology and treatment of the condition.Nonetheless, pruritus remains poorly understood\nand many patients continue to suffer, reiterating the need for further research to improve our understanding of the etiology and\ntreatment for the condition.
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